Saint Mary, officially the Parish of Saint Mary, is a parish of Antigua and Barbuda on the island of Antigua. Saint Mary borders Saint John to the north, and Saint Paul to the east. Saint Mary is dominated by the Shekerley Mountains, and its northern border is largely defined by the mountains, and by Cooks Creek. The largest city in the parish is Bolans, home to the Jolly Harbour neighbourhood, and the parish church is located in Old Road. Saint Mary was created with the other five original parishes on 11 January 1692. It had a population of 7,341 in 2011, and 8,141 in 2018.

Antigua and Barbuda is a sovereign island country in the Caribbean. It lies at the conjuncture of the Caribbean Sea and the Atlantic Ocean in the Leeward Islands part of the Lesser Antilles.