St. Patrick's Cathedral is the seat of the Roman Catholic Archdiocese of Karachi, and is located near the Empress Market in the Saddar locality in central Karachi. The church was completed in 1881, and can accommodate 1,500 worshipers. At the front of the cathedral, there is the Monument to Christ the King, built between 1926 and 1931 to commemorate the Jesuit mission in Sindh.

The Archdiocese of Karachi is a Latin Church ecclesiastical territory or archdiocese of the Catholic Church in Pakistan. It was erected on 20 May 1948 under as a then-suffragan diocese in the ecclesiastical province of the metropolitan Archdiocese of Bombay.