Saiyuki Reload Gunlock is a sequel and the third season of the Saiyuki anime television series produced by Studio Pierrot. Adapted from the manga of Saiyuki Reload by Kazuya Minekura, the series is directed by Tetsuya Endo, written by Tetsuya Endo and composed by Daisuke Ikeda.

Saiyuki is a Japanese manga series written and illustrated by Kazuya Minekura. It was originally serialized in Square Enix's shōnen manga magazine Monthly GFantasy between February 1997 and November 2001, with its chapters collected in nine tankōbon volumes; and later republished by Ichijinsha, released the nine volumes with new covers from October 2002 to June 2003; and published a new edition in 2015. The story, which is loosely based on the 16th-century Chinese novel Journey to the West, follows a monk named Genjo Sanzo who receives a mission to travel to the west with a group of three yokai (demons) to stop anyone reviving the evil god Gyumao.