The Salamaua–Lae campaign was a series of actions in the New Guinea campaign of World War II. Australian and United States forces sought to capture two major Japanese bases, one in the town of Lae, and another one at Salamaua. The campaign to take the Salamaua and Lae area began after the successful defence of Wau in late January, which was followed up by an Australian advance towards Mubo as the Japanese troops that had attacked Wau withdrew to positions around Mubo. A series of actions followed over the course of several months as the Australian 3rd Division advanced north-east towards Salamaua. After an amphibious landing at Nassau Bay, the Australians were reinforced by a US regimental combat team, which subsequently advanced north up the coast.

The New Guinea campaign of the Pacific War lasted from January 1942 until the end of the war in August 1945. During the initial phase in early 1942, the Empire of Japan invaded the Territory of New Guinea on 23 January and Territory of Papua on 21 July and overran western New Guinea beginning on 29 March. During the second phase, lasting from late 1942 until the Japanese surrender, the Allies—consisting primarily of Australian forces—cleared the Japanese first from Papua, then New Guinea, and finally from the Dutch colony.