The Salamaua–Lae campaign was a series of actions in the New Guinea campaign of World War II. Australian and United States forces sought to capture two major Japanese bases, one in the town of Lae, and another one at Salamaua. The campaign to take the Salamaua and Lae area began after the successful defence of Wau in late January, which was followed up by an Australian advance towards Mubo as the Japanese troops that had attacked Wau withdrew to positions around Mubo. A series of actions followed over the course of several months as the Australian 3rd Division advanced north-east towards Salamaua. After an amphibious landing at Nassau Bay, the Australians were reinforced by a US regimental combat team, which subsequently advanced north up the coast.

Lae is the capital of Morobe Province and is the second-largest city in Papua New Guinea. It is located near the delta of the Markham River and at the start of the Highlands Highway, which is the main land transport corridor between the Highlands Region and the coast. Lae is the largest cargo port of the country and is the industrial hub of Papua New Guinea. The city is known as the Garden City and home of the University of Technology.