Saline County is a county located in the U. S. state of Arkansas. As of the 2010 census, the population was 107,118. At the 2010 census, its county seat and largest city is Benton. Saline County was formed on November 2, 1835, named for the salt water springs in the area, however, it is pronounced "suh-LEAN" instead of the typical pronunciation, "SAY-lean"; until November 2014, it was dry county. Saline County is included in the Little Rock–North Little Rock–Conway, AR Metropolitan Statistical Area. According to the U. S. Census Bureau, the county has a total area of 730 square miles, of which 724 square miles is land and 6.9 square miles is water. Interstate 30 Interstate 30 Business Loop Interstate 530 U. S. Highway 65 U. S. Highway 67 U. S. Highway 70 U. S. Highway 167 Highway 5 Highway 9 Highway 35 Perry County Pulaski County Grant County Hot Spring County Garland County Ouachita National Forest As of the 2000 United States Census, there were 83,529 people, 31,778 households, 24,500 families residing in the county.

The population density was 116 people per square mile. There were 33,825 housing units at an average density of 47 per square mile; the racial makeup of the county was 95.27% White, 2.20% Black or African American, 0.49% Native American, 0.57% Asian, 0.03% Pacific Islander, 0.45% from other races, 1.00% from two or more races. 1.30 % of the population were Latino of any race. There were 31,778 households out of which 35.40% had children under the age of 18 living with them, 63.80% were married couples living together, 9.70% had a female householder with no husband present, 22.90% were non-families. 19.60% of all households were made up of individuals and 7.50% had someone living alone, 65 years of age or older. The average household size was 2.57 and the average family size was 2.94. In the county, the population was spread out with 25.50% under the age of 18, 7.70% from 18 to 24, 30.20% from 25 to 44, 24.20% from 45 to 64, 12.50% who were 65 years of age or older. The median age was 37 years.

For every 100 females, there were 98.10 males. For every 100 females age 18 and over, there were 95.30 males. The median income for a household in the county was $42,569, the median income for a family was $48,717. Males had a median income of $32,052 versus $23,294 for females; the per capita income for the county was $19,214. About 5.00% of families and 7.20% of the population were below the poverty line, including 8.80% of those under age 18 and 7.30% of those age 65 or over. The area is in print by The Saline Courier. Over The past few election cycles Saline County has trended towards the GOP; the last democrat to carry this county was Bill Clinton in 1996. Alexander Benton Bryant Haskell Shannon Hills Traskwood Bauxite Avilla East End Hot Springs Village Salem Brooks Lakeside Owensville Paron Townships in Arkansas are the divisions of a county; each township includes unincorporated areas. Arkansas townships have limited purposes in modern times. However, the United States Census does list Arkansas population based on townships.

Townships are of value for historical purposes in terms of genealogical research. Each town or city is within one or more townships in an Arkansas county based on census maps and publications; the townships of Saline County are listed below. Source: List of lakes in Saline County, Arkansas National Register of Historic Places listings in Saline County, Arkansas Lanny Fite GovernmentSaline County Sheriff's OfficeGeneral information Geographic data related to Saline County, Arkansas at OpenStreetMap Saline County, Arkansas at ARGenWeb Saline County at Encyclopedia of Arkansas History & Culture Saline County in the Civil War at The Historical Marker Database Saline County Library

Johann Sebastian Bach composed the church cantata Was willst du dich betrüben, BWV 107 in Leipzig for the seventh Sunday after Trinity and first performed on 23 July 1724. The chorale cantata is based on the words of Johann Heermann's hymn in seven stanzas "Was willst du dich betrüben". Bach structured the cantata, the seventh work in his chorale cantata cycle, in seven movements: two framing choral movements, a recitative and an unusual sequence of four bipartite arias, he scored the work for three vocal soloists, a four-part choir, a Baroque chamber ensemble of a horn to reinforce the hymn tune in the outer movements, two transverse flutes, two oboes d'amore and continuo. It is the only known work from his chorale cantata cycle. Bach composed the chorale cantata in Leipzig for the Seventh Sunday after Trinity; the prescribed readings for the Sunday are from the Epistle to the Romans, "I speak in human terms because of your human limitations... the wages of sin is death. The cantata is based on Johann Heermann's hymn in seven stanzas, "Was willst du dich betrüben", focused on trust in God when facing adversaries including the devil.

Trust in God is a theme of the Gospel. Unusually for a chorale cantata of the second cycle, the text is not changed in the middle movements, but kept "per omnes versus"; the middle movements are, composed as a recitative and four arias. The treatment was decidedly old-fashioned in Bach's time, he had used it once much earlier in Christ lag in Todes Banden, BWV 4, again as in Gelobet sei der Herr, mein Gott, BWV 129, though it was not repeated during the second cycle. John Eliot Gardiner assumes that Bach imposed this restriction on himself, as he had done with the restriction to place the cantus firmus in soprano, alto and bass in the first four cantatas of the cycle. Gardiner comments on the "seventeenth-century design" of composing the unchanged chorale text, compared to settings of Stölzel and Graupner: But only Bach is prepared to make life difficult for himself, as here, for example, by choosing to incorporate verbatim all seven stanzas of a rather obscure chorale by Johann Heermann from 1630.

… Bach rises to the challenge: to overcome the limitations of being confined to a rigidly structured hymn without monotony or repetitiveness. The chorales in Heermann's 1630 publication Devoti musica cordis, which included "Herzliebster Jesu, was hast du verbrochen", the first chorale in Bach's St Matthew Passion, have been described as "the first in which the correct and elegant versification of Opitz was applied to religious subjects, … distinguished by great depth and tenderness of feeling, by an intense love of the Saviour, earnest but not self-conscious humility". Bach first performed the cantata, the seventh extant cantata of his second annual cycle, on 23 July 1724. Bach structured the cantata in seven movements, beginning with a chorale fantasia and ending in a closing chorale, as in his chorale cantatas, but with an unusual sequence of only one recitative and four arias, setting the poetic hymn stanzas, he scored it for three vocal soloists, a four-part choir, a Baroque chamber ensemble of corno da caccia to support the chorale tune in the outer movements, two flauti traversi, two oboes d'amore, two violins, two violas and basso continuo.

In the following table of the movements, the scoring follows the Neue Bach-Ausgabe, the keys are given for the Weimar version. The time signature is provided using the symbol for common time; the opening chorus, "Was willst du dich betrüben", is a chorale fantasia, with the vocal part embedded in an independent concerto of the instruments. The cantus firmus on the melody of "Von Gott will ich nicht lassen" is in long notes embellished, in the soprano and horn; the lines of the chorale are not rendered separately, but accenting the bar form of the text, 1 and 2 are combined, 3 and 4 are combined, 5 is single and 6 to 8 are combined. The scoring is rich in woodwinds; the only recitative, "Denn Gott verlässet keinen, der sich auf ihn verläßt", is accompanied by the oboes d'amore, shows an extended melisma on the word "Freuden" and culminates in an arioso in the final line, with a melisma on retten. The following four stanzas are composed as arias, not as the typical da capo arias, but in two parts.

Bach achieves variation by changing voice type and time signature. He varies the mode, alternating major and minor keys, expresses different affekts, he "blurs" the bar form of the stanzas; the first aria, depicts a "hunting scene" for bass and strings. Bach plays on the double meaning of the German word erjagen, which in the text has the sense "achieve by great exertion", but he expresses the word's literal meaning by an "outrageous hunting call trill" of the bass; this aria and those following are not da capo arias, but follow the bar form of the poem as bipartite structures. The second aria, "Wenn auch gleich aus der Höllen", for tenor and continuo begins with strong words on Satan as an enemy: "Wenn auch gleich aus der Höllen / der Satan wollte sich / dir selbst entgegenstellen / und toben wider dich" ("Even if, out of hell, Satan wishes to set himself against you, vent his

Pallacanestro Treviso, named Benetton Basket due to a long running sponsorship by the Benetton Group and referred to as Benetton Treviso, is an Italian youth basketball club based in Treviso, Veneto. The club was a successful professional club until 2012 when the Benetton Group decided to withdraw from professional basketball, though they retained the youth section at La Ghirada, the sports complex they own. For past club sponsorship names, see sponsorship names. Founded in 1954 as Duomo Folgore, it remained in obscurity for the first few decades of its existence though it did reach the first division Lega Basket Serie A in 1962; however the club only stayed there one season, finishing the league in last place, after which it was hampered by financial problems. Duomo Folfore was renamed Associazione Pallacanestro Treviso sometime during the 1970s, with new ownership, it moved up the divisions, reaching the national Serie A2 in 1979. In 1980-81 the team finished third in the league, earning a return to the Serie A.

The Benetton Group started sponsoring the club during the 1981-82 season, which ended with a relegation to the A2. The following year, Benetton would become the majority owners of Pallacanestro Treviso, moving into the newly constructed PalaVerde and financed by the family. Promoted in 1985, it stayed in Serie A one-season before going back down. Another promotion followed in 1987, this one would see the club start a permanent stay in the elite. In 1991, the club became Pallacanestro Treviso, with its status changing from an association to a limited liability company; that year would spark a new era for Benetton Basket, with the arrival of the legendary Toni Kukoč from the three-peat European Champions of Pop 84, but of Stefano Rusconi from Cagiva Varese and Nino Pellacani, the team would beat Scavolini Pesaro to win their first Serie A title in 1992. The next season, Benetton won the Italian Cup and reached the Final Four of the FIBA European League that take place in Peace and Friendship Stadium, in the semifinal defeated PAOK 79–77.

In the final, Benetton although it was the favorite of the match, lost to Limoges CSP 55–59. Though Kukoč left for the NBA in the summer, Riccardo Pittis joined the club that won another Italian Cup that year, they would win their first European title, the FIBA European Cup against Taugrés, in 1995, thanks to players such as Orlando Woolridge and Petar Naumoski, became third successive Italian Cup that garnished the trophy cabinet. Benetton added another Serie A title in 1997, a second FIBA Saporta Cup in 1999 against Pamesa Valencia, an Italian cup in 2000. During the 2001 -- 02 season they won the league; the next year they did better with a treble, winning the Supercup and league but they didn't manage to won the Euroleague title defeated in the final by FC Barcelona. Adding more league titles after that, Benetton Basket reached the Euroleague Final Four on a few occasions but never managed to win the title. In February 2011, the Benetton family announced they would be withdrawing their support for professional basketball calling time on Treviso's top flight status if no other backer could be found.

Well-wishers such as former players Paolo Vazzoler and Pittis tried to rouse support for a new club, Treviso Basket 2012. However their application to take Benetton Basket's place in the Serie A was rejected. Since Benetton Basket has focused only on youth development, with the Under 17 squad their most senior. Treviso is represented in professional basket by Universo Treviso Basket - the renamed Treviso Basket 2012 - who, as of June 2015, play in the second division. Total titles: Italian LeagueWinners: 1991–92, 1996–97, 2001–02, 2002–03, 2005–06 Runners-up: 1992–93, 1994–95, 1998–99, 1999–00Italian CupWinners: 1992–93, 1993–94, 1994–95, 1999–00, 2002–03, 2003–04, 2004–05, 2006–07 Runners-up: 1991–92, 1997–98Italian SupercupWinners: 1997, 2001, 2002, 2006 Runners-up: 1995, 2003, 2004, 2005, 2007 EuroLeagueRunners-up: 1992–93, 2002–03 3rd place: 1997–98, 2001–02 Final Four: 1993, 1998, 2002, 2003FIBA Saporta Cup Winners: 1994–95, 1998–99FIBA Korać Cup Semifinalists: 1996–97EuroCup Basketball4th place: 2010–11 FIBA International Christmas Tournament 4th place: 1991 Mario De Sisti Piero Pasini Gianmaria Conte Gianfranco Lombardi Mauro Di Vincenzo Massimo Mangano Lajos Toth Riccardo Sales Emanuele Molin Petar Skansi Fabrizio Frates Mike D'Antoni Željko Obradović Piero Bucchi Ettore Messina David Blatt Alessandro Ramagli Oktay Mahmuti Jasmin Repeša Aleksandar Đorđević Throughout the years, due to sponsorship, the club has been known as: Faram Treviso Liberti Treviso Benetton Basket Official website 2011–12 Eurocup profile

The 1992 Philadelphia Phillies season was a season in Major League Baseball. The Phillies finished sixth in the National League East with a record of 92 losses. December 8, 1991: Von Hayes was traded by the Phillies to the California Angels for Rubén Amaro, Jr. and Kyle Abbott. December 9, 1991: Danny Cox was signed as a free agent by the Phillies. December 10, 1991: Mariano Duncan was signed as a free agent by the Phillies. December 11, 1991: Bruce Ruffin was traded by the Phillies to the Milwaukee Brewers for Dale Sveum. January 8, 1992: The Phillies traded a player to be named to the New York Yankees for Darrin Chapin; the Phillies completed the deal by sending Charlie Hayes to the Yankees on February 19. January 8, 1992: Rick Schu was signed as a free agent by the Phillies. On September 20, Mickey Morandini executed an unassisted triple play in the sixth inning, he caught a line drive, tagged the runner coming from first base. April 2, 1992: Jason Grimsley was traded by the Phillies to the Houston Astros for Curt Schilling.

April 5, 1992: Steve Lake was signed as a free agent by the Phillies. June 1, 1992: Bobby Estalella was drafted by the Phillies in the 23rd round of the 1992 Major League Baseball draft. Player signed May 9, 1993. June 7, 1992: Danny Cox was released by the Phillies. August 10, 1992: Dale Sveum was traded by the Phillies to the Chicago White Sox for Keith Shepherd. August 11, 1992: Steve Scarsone was traded by the Phillies to the Baltimore Orioles for Juan Bell. Note: Pos = Position. = Batting average. = Batting average.

Cardamine pratensis, is a flowering plant in the family Brassicaceae, native throughout most of Europe and Western Asia. The specific name pratensis is Latin for "meadow." Cardamine pratensis is a herbaceous, perennial plant growing to 40–60 cm tall, with pinnate leaves 5–12 cm long with 3–15 leaflets, each leaflet about 1 cm long. The flowers are produced on a spike 10–30 cm long, each flower 1–2 cm in diameter with four pale violet-pink petals; the style of the fruit is longish. It grows best close to water, its common name cuckooflower derives from the formation of the plant's flowers at around the same time as the arrival each spring of the first cuckoos in the British Isles. The species is found throughout the British Isles. Recorded in Ireland from all 40 of the "vice-counties", it is grown as an ornamental plant in gardens, has become naturalised in North America as a result of cultivation. In some European countries, including parts of Germany, the plant is now under threat, it is a food plant for the orange tip butterfly and makes a valuable addition to any garden which aims at attracting wildlife.

It was once used as a substitute for watercress. In folklore it was said to be sacred to the fairies, so was unlucky if brought indoors, it was not included in May Day garlands for the same reason. It is the county flower of the English county of Cheshire. Blanchan, Neltje. Wild Flowers: An Aid to Knowledge of our Wild Flowers and their Insect Visitors. Project Gutenberg Literary Archive Foundation

Programmed cell death 1 ligand 2 is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has been designated as CD273. PDCD1LG2 is an immune checkpoint receptor ligand which plays a role in negative regulation of the adaptive immune response. PD-L2 is one of two known ligands for Programmed cell death protein 1. PD-L2 is a cell surface receptor belonging to the B7 protein family, it consists of both an immunoglobulin-like variable domain and an immunoglobulin-like constant domain in the extracellular region, a transmembrane domain, a cytoplasmic domain. PD-L2 shares considerable sequence homology with other B7 proteins, but it does not contain the putative binding sequence for CD28/CTLA4, namely SQDXXXELY or XXXYXXRT; the crystal structure of murine PD-L2 bound to murine PD-1 has been determined. As well as the structure of the hPD-L2/mutant hPD-1 complex. PD-L2 is expressed on professional antigen presenting cells including dendritic cells and macrophages. Others have shown PD-L2 expression in certain T helper cell subsets and cytotoxic T cells.

PD-L2 protein is expressed in many healthy tissues including the GI tract tissues, skeletal muscles and pancreas. Additionally, PD-L2 has moderate to high expression in triple-negative breast cancer and gastric cancer and low expression in renal cell carcinoma. PD-L2 mRNA is expressed and not enriched in any particular tissue. Interleukin-4 and granulocyte-macrophage colony stimulating factor both upregulate PD-L2 expression in DCs in vitro. IFN-α, IFN-β, IFN-γ induce moderate upregulation of PD-L2 expression. PD-L2 binds to its receptor PD-1 with dissociation constant Kd of 11.3 nM. Binding to PD-1 can activate pathways inhibiting TCR/BCR-mediated immune cell activation. PD-L2 plays an important role in immune autoimmunity. Both PD-L1 and PD-L2 can inhibit inflammatory cytokine production. Blocking PD-L2 has been shown to exacerbate experimental autoimmune encephalomyelitis. Unlike PD-L1, PD-L2 has been shown activate the immune system. PD-L2 triggers IL-12 production in murine dendritic cells leading to T cell activation.

Others have shown. PD-L2, PD-L1, PD-1 expressions are important in the immune response to certain cancers. Due to their role in suppressing the adaptive immune system, efforts have been made to block PD-1 and PD-L1, resulting in FDA approved inhibitors for both. There are still no FDA approved inhibitors for PD-L2 as of 2019; the direct role of PD-L2 in cancer progression and immune-tumor microenvironment regulation is not as well studied as the role of PD-L1. In mouse cell cultures, PD-L2 expression on tumor cells suppressed cytotoxic T cell-mediated immune responses. Indirectly, PD-L2 may have utility as prognostic indicator. PD-L2 expression has been shown to predict response to PD-1 blockade with pembrolizumab independently of PD-L1 expression. However, PD-L2 does not putatively predict outcome in cancer, with some studies suggesting it predicts negative prognoses and other studies suggesting it predicts positive prognoses. PDCD1LG2+protein,+human at the US National Library of Medicine Medical Subject Headings