Salisbury was a house and plantation in northwestern Chesterfield County, Virginia in the Southside area of Metro Richmond, Virginia. It was most likely built in the early 1760s by Abraham Salle (c.1732-c.1800), a descendant of Huguenot refugees fleeing persecution in France. Salle's grandfather, also named Abraham (1670–1719), was the immigrant ancestor for most of the Huguenot Salles living in Colonial Virginia. Abraham Salle had "assembled the original 1,500 acre tract between 1760 to 1763" from various parcels of land primarily owned by his uncles William and Robert Wooldridge. The Wooldridges had inherited the land from their father, John "Blacksmith" Wooldridge (c.1678-1757), himself the immigrant ancestor of all Wooldridges living in the American South.

Patrick Henry was an American politician, planter and orator who declared to the Second Virginia Convention (1775): "Give me liberty, or give me death!" A Founding Father, he served as the first and sixth post-colonial Governor of Virginia, from 1776 to 1779 and from 1784 to 1786.