Saltram House is a grade I listed George II era house in Plympton, Devon, England. It was deemed by the architectural critic Pevsner to be "the most impressive country house in Devon". The house was designed by the architect Robert Adam, who altered and greatly expanded the original Tudor house on two occasions. The Saloon is considered one of Adam's finest interiors. Saltram is one of Britain's best preserved examples of an early Georgian house and retains much of its original decor, plasterwork and furnishings. It contains the Parker family's large collection of paintings, including several by Sir Joshua Reynolds (1723-1792), born and educated at Plympton and a friend of the Parker family.

Plympton is a suburb of the city of Plymouth in Devon, England. It is in origin an ancient stannary town. It was an important trading centre for locally mined tin, and a seaport before the River Plym silted up and trade moved down river to Plymouth and was the seat of Plympton Priory the most significant local landholder for many centuries.