Salvatore Inzerillo was an Italian member of the Sicilian Mafia, also known as Totuccio. He rose to be a powerful boss of Palermo's Passo di Rigano family. A prolific heroin trafficker, he was killed in May 1981 by a firing squad of the Corleonesi family led by Totò Riina during the Second Mafia War who opposed the established Palermo Mafia families of which Inzerillo was one of the main proponents.

The Sicilian Mafia Commission, known as Commissione or Cupola, is a body of leading Sicilian Mafia members who decide on important questions concerning the actions of, and settling disputes within the Sicilian Mafia or Cosa Nostra. It is composed of representatives of a mandamento who are called capo mandamento or rappresentante. The Commission is not a central government of the Mafia, but a representative mechanism for consultation of independent Mafia families who decide by consensus. Its primary role is to keep the use of violence among families within limits tolerable to the public and political authorities.