Salvatore "Good Looking Sal" Vitale is an American former underboss of the Bonanno crime family before he became a government informant. After his arrest in 2003, Vitale agreed to cooperate with the government and testify against his brother-in-law, boss Joseph Massino, and in July 2004, Massino was convicted in a RICO case. Vitale had admitted to 11 murders, however, in October 2010, was sentenced to time served due to his cooperation, and entered the witness protection program.

The Bonanno crime family is an Italian-American Mafia crime family and one of the "Five Families" that dominate organized crime activities in New York City, and in the United States, as part of the criminal phenomenon known as the American Mafia.