Sam Ratulangi University is a state university in Manado, North Sulawesi, Indonesia. It was established on September 14, 1965. The current rector is Prof. Dr. Ir. Oktovian Berty Alexander Sompie, M.Eng., IPU, ASEAN Eng.

Gerungan Saul Samuel Jacob Ratulangi, known as Sam Ratulangi, was a Minahasan teacher, journalist, politician, and national hero from North Sulawesi, Indonesia. He was part of the committee that ratified the Constitution of Indonesia and served as the first Governor of Sulawesi.