Sam Burke and Maximilian "Twitch" Williams are two fictional NYPD homicide detectives, created by Todd McFarlane. Sam and Twitch were originally featured in McFarlane's hit comic series Spawn. Due to their popularity, they were later given their own title in 1999, called Sam and Twitch. In their self-titled series, the duo were the protagonists in a dark and gritty New York City. The fictional universe of Sam and Twitch is somewhat different from average comics in which costumed heroes are not the norm.

Todd McFarlane is a Canadian comic book creator, best known for his work as the artist on The Amazing Spider-Man and as the creator, writer, and artist on the superhero horror-fantasy series Spawn, as well as being the current President and a co-founder of Image Comics.