Samlesbury is a village and civil parish in South Ribble, Lancashire, England. Samlesbury Hall, a historic house, is in the village, as is Samlesbury Aerodrome and a large modern brewery owned by Anheuser-Busch InBev. The population at the 2011 census was 1,206.

South Ribble is a local government district with borough status in Lancashire, England. Its council is based in Leyland. The borough also includes the towns and villages of Penwortham, Leyland, Farington, Hutton, Longton, Walmer Bridge, Salmesbury, Lostock Hall, Walton le Dale and Bamber Bridge. Many of the built-up areas in the borough form part of the wider Preston built-up area.