Samsu-iluna was the seventh king of the founding Amorite dynasty of Babylon, ruling from 1749 BC to 1712 BC, or from 1686 to 1648 BC. He was the son and successor of Hammurabi by an unknown mother. His reign was marked by the violent uprisings of areas conquered by his father and the abandonment of several important cities.

Babylon was an ancient city located on the lower Euphrates river in southern Mesopotamia, within modern-day Hillah, Babil Governorate, Iraq about 85 kilometers south of modern day Baghdad. Babylon functioned as the main cultural and political centre of the Akkadian-speaking region of Babylonia. Its rulers establishing two important empires in antiquity, the 19th–16th century BC Old Babylonian Empire, and the 7th–6th century BC Neo-Babylonian Empire. Babylon was also used as a regional capital of other empires, such as the Achaemenid Empire. Babylon was one of the most important urban centres of the ancient Near East, until its decline during the Hellenistic period. Nearby ancient sites are Kish, Borsippa, Dilbat, and Kutha.