The San'yō Main Line is a major railway line owned by JR Group companies in western Japan, connecting Kōbe Station and Moji Station, largely paralleling the coast of the Seto Inland Sea, in other words, the southern coast of western Honshu. The San'yō Shinkansen line largely parallels its route. The name Sanyō derived from the ancient region and highway San'yōdō, the road on the sunny (south) side of the mountains.

Kobe Station is a railway station in Chūō-ku, Kobe, Japan, operated by West Japan Railway Company. Although Kobe Station is the namesake of the city of Kobe, Kobe City Hall and the commercial center of Kobe is closer to Kobe-Sannomiya Station.