The San Angelo metropolitan statistical area (MSA) is a metropolitan area in West Texas that covers two counties - Tom Green and Irion. As of the 2010 census, the MSA had a population of 111,823, with a 2014 estimate of 118,182.

Tom Green County is a county located on the Edwards Plateau in the U.S. state of Texas. As of the 2020 census, its population was 120,003. Its county seat is San Angelo. The county was created in 1874 and organized the following year. It is named for Thomas Green, who was a Confederate soldier and lawyer. Tom Green County is included in the San Angelo metropolitan statistical area; the county is home to Goodfellow Air Force Base, as well as Angelo State University, part of the Texas Tech University System.