San Antón is one of the 31 barrios of the municipality of Ponce, Puerto Rico. Along with Canas Urbano, Machuelo Abajo, Magueyes Urbano, and Portugués Urbano, San Antón is one of the municipality's five originally rural barrios that are now also part of the urban zone of the city of Ponce. It is totally enclosed within the Ponce city limits. It was founded in 1818.

The barrios of Puerto Rico are the primary legal divisions of the seventy-eight municipalities of Puerto Rico. Puerto Rico's 78 municipios are divided into geographical sections called barrios and, as of 2010, there were 902 of them. In the US Census a barrio sometimes includes a division called a comunidad or subbarrio. In Puerto Rico, barrios are composed of sectors. The types of sectors (sectores) may vary, from normally sector to urbanización to reparto to barriada to residencial, among others.