San Bruno station is a Caltrain station located in San Bruno, California. The station is located just northeast of downtown San Bruno, above the intersection of San Mateo and San Bruno Avenues, adjacent to Artichoke Joe's Casino.

The Third and Townsend Depot was the main train station in the city of San Francisco for much of the first three quarters of the 20th century. The station at Third Street and Townsend Street served as the northern terminus for Southern Pacific's Peninsula Commute line between San Francisco and San Jose and long-distance trains between San Francisco and Los Angeles via the Southern Pacific's Coast Line. For service for destinations to the north, such as Seattle, and destinations to the east, such as Chicago, passengers generally needed to travel to Oakland, initially on ferries to Oakland Long Wharf, and later on buses to 16th Street Station. It was demolished in the 1970s and replaced by the Caltrain commuter station a block away at Fourth and King Streets.