San Carlos Cathedral, officially known as the San Carlos Borromeo Cathedral Parish, is a 20th-century Eclectic Roman Catholic cathedral parish dedicated to Saint Charles Borromeo, located in the city proper of San Carlos, Negros Occidental, region of Western Visayas, Philippines. In 1987, it became the cathedral of the Diocese of San Carlos which comprises northeastern Negros Occidental and northern Negros Oriental.

San Carlos, officially the City of San Carlos, is a second-class component city in the province of Negros Occidental in the Philippines. According to the 2020 census, it has a population of 132,650 people.