San Diego Bay is a natural harbor and deepwater port located in San Diego County, California near the U.S.–Mexico border. The bay, which is 12 miles (19 km) long and 1 to 3 miles wide, is the third largest of the three large, protected natural bays on California's 840 miles (1,350 km) of coastline, after San Francisco Bay and Humboldt Bay. The highly urbanized land adjacent to the bay includes the city of San Diego and four other cities: National City, Chula Vista, Imperial Beach and Coronado.

San Diego County, officially the County of San Diego, is a county in the southwestern corner of the U.S. state of California. As of the 2020 census, the population was 3,298,634, making it California's second-most populous county and the fifth-most populous in the United States. Its county seat is San Diego, the second-most populous city in California and the eighth-most populous city in the United States. It is the southwesternmost county in the 48 contiguous United States, and is a border county. It is also home to 18 Native American tribal reservations, the most of any county in the United States.