San Felipe is a commune and the capital city of the San Felipe de Aconcagua Province in central Chile's Valparaíso Region. Until 1976, it was the capital of Aconcagua province, a first-level administrative division. It lies 88 km (55 mi) north of the national capital of Santiago. The commune spans an area of 185.9 km2 (72 sq mi).

The Valparaíso Region is one of Chile's 16 first order administrative divisions. With the country's second-highest population of 1,790,219 as of 2017, and fourth-smallest area of 16,396.1 km2 (6,331 sq mi), the region is Chile's second most densely populated after the Santiago Metropolitan Region to the southeast. The region also includes Chile's remote islands of the Pacific Ocean, including Rapa Nui and the Juan Fernandez Islands.