The San Francisco District Attorney's Office is the legal agency charged with prosecuting crimes in the City and County of San Francisco, California. The current district attorney is Brooke Jenkins. Occupants of this office have gone on to higher elected offices, including: governor of California, United States Senator, and vice president of the United States.

Brooke Jenkins is an American lawyer serving as the 30th District Attorney of San Francisco. On July 8, 2022, Jenkins was appointed interim district attorney by Mayor London Breed following the successful recall of Chesa Boudin, for which she actively campaigned. She was elected in her own right to fill the unexpired term the following November.