The San Francisco Symphony, founded in 1911, is an American orchestra based in San Francisco, California. Since 1980 the orchestra has been resident at the Louise M. Davies Symphony Hall in the city's Hayes Valley neighborhood. The San Francisco Symphony Youth Orchestra and the San Francisco Symphony Chorus (1972) are part of the organization. Michael Tilson Thomas became the orchestra's music director in 1995, and concluded his tenure in 2020 when Esa-Pekka Salonen took over the position.

San Francisco, officially the City and County of San Francisco, is a commercial, financial, and cultural center in Northern California. With a population of 808,437 residents as of 2022, San Francisco is the fourth most populous city in the U.S. state of California. The city covers a land area of 46.9 square miles at the end of the San Francisco Peninsula, making it the second-most densely populated large U.S. city after New York City and the fifth-most densely populated U.S. county, behind only four New York City boroughs. Among the 92 U.S. cities proper with over 250,000 residents, San Francisco is ranked first by per capita income and sixth by aggregate income as of 2022.