San Pedro de Macorís is a city and municipality (municipio) in the Dominican Republic and the capital of the San Pedro de Macorís province in the east region of the country; it is among the 10 largest cities of the Dominican Republic. The city has approximately 217,000 inhabitants, when including the whole municipality. As a provincial capital, it houses the Universidad Central del Este university.

San Pedro de Macorís is a province of the Dominican Republic, also the name of its capital city. The city is fairly active due to its proximity to the national capital of Santo Domingo and also its role in the sugar industry. The province is informally known as San Pedro, SPM or Serie 23 for the first two numbers of their Dominican identification or Cedula.