San Timoteo Canyon is a river valley canyon southeast of Redlands, in the far northwestern foothills of the San Jacinto Mountains in the Inland Empire region of Southern California.

The Cahuilla, also known as ʔívil̃uqaletem or Ivilyuqaletem, are a Native American people of the various tribes of the Cahuilla Nation, living in the inland areas of southern California. Their original territory included an area of about 2,400 square miles (6,200 km2). The traditional Cahuilla territory was near the geographic center of Southern California. It was bounded to the north by the San Bernardino Mountains, to the south by Borrego Springs and the Chocolate Mountains, to the east by the Colorado Desert, and to the west by the San Jacinto Plain and the eastern slopes of the Palomar Mountains.