The Legazpi-Sikatuna Blood Compact or Sandugo was a blood compact, performed in the island of Bohol in the Philippines, between the Spanish explorer Miguel López de Legazpi and Datu Sikatuna, chieftain of Bohol, on March 16, 1565, to seal their friendship following tribal tradition. This is considered the first treaty of friendship between the Spaniards and Filipinos. "Sandugo" is a Visayan word which means "one blood".

Bohol, officially the Province of Bohol, is an island province of the Philippines located in the Central Visayas region, consisting of the island itself and 75 minor surrounding islands. Its capital is Tagbilaran. With a land area of 4,821 km2 (1,861 sq mi) and a coastline 261 km (162 mi) long, Bohol is the tenth largest island of the Philippines.