Sandy Creek is an 18.5-mile-long (29.8 km) creek located entirely within Monroe County in the U.S. state of Michigan. The creek rises in London Township in the north-central portion of the county and flows southeast into Lake Erie in Frenchtown Charter Township at Sterling State Park.

Monroe County is a county in the U.S. state of Michigan. As of the 2020 Census, the population was 154,809. The largest city and county seat is Monroe. The county was established as the second county in the Michigan Territory in 1817 and was named for then-President James Monroe. Monroe County is coterminous with the Monroe metropolitan statistical area.