Sanford is a city and the county seat of Seminole County, Florida. It is located in Central Florida and its population was 61,051 as of the 2020 census. It is part of the Orlando–Kissimmee–Sanford Metropolitan Statistical Area.

Seminole County is a county located in the central portion of the U.S. state of Florida. As of the 2020 census, the population was 470,856, making it the 13th-most populated county in Florida. Its county seat and largest city is Sanford. Seminole County is part of the Orlando-Kissimmee-Sanford, Florida Metropolitan Statistical Area.