Santa Barbara Island is a small island of the Channel Islands archipelago in Southern California. It is protected within Channel Islands National Park, and its marine ecosystem is part of the Channel Islands National Marine Sanctuary.

The Channel Islands are an eight-island archipelago located within the Southern California Bight in the Pacific Ocean, off the coast of California. They define the Santa Barbara Channel, which sits between the islands and the California mainland. The four Northern Channel Islands are part of the Transverse Ranges geologic province, and the four Southern Channel Islands are part of the Peninsular Ranges province. Five of the islands are within the Channel Islands National Park, and the waters surrounding these islands make up Channel Islands National Marine Sanctuary. The Nature Conservancy was instrumental in establishing the Channel Islands National Marine Sanctuary.