Santa Cruz is a district in the northern part of the City of Manila, Philippines, located on the right bank of the Pasig River near its mouth, bordered by the districts of Tondo, Binondo, Quiapo, and Sampaloc, as well as the areas of Grace Park and Barrio San Jose in Caloocan and the district of La Loma in Quezon City. The district belongs to the 3rd congressional district of Manila.

The Department of Health is the executive department of the government of the Philippines responsible for ensuring access to basic public health services by all Filipinos through the provision of quality health care, the regulation of all health services and products. It is the government's over-all technical authority on health. It has its headquarters at the San Lazaro Compound, along Rizal Avenue in Manila.