Santa Cruz de Nuca was a Spanish colonial fort and settlement and the first European colony in what is now known as British Columbia. The settlement was founded on Vancouver Island in 1789 and abandoned in 1795, with its far northerly position making it the "high-water mark" of verified northerly Spanish settlement along the North American west coast. The colony was established with the Spanish aim of securing the entire west coast of the continent from Alaska southwards, for the Spanish crown.

Vancouver Island is an island in the northeastern Pacific Ocean and part of the Canadian province of British Columbia. The island is 456 km (283 mi) in length, 100 km (62 mi) in width at its widest point, and 32,100 km2 (12,400 sq mi) in total area, while 31,285 km2 (12,079 sq mi) are of land. The island is the largest by area and the most populous along the west coasts of the Americas.