Santa Fe Springs is a city in Los Angeles County, California, United States. It is one of the Gateway Cities of southeast Los Angeles County. The population was 16,223 at the 2010 census, down from 17,438 in the 2000 census.

The Gateway Cities Region, or Southeast Los Angeles County, is an urbanized region located in southeastern Los Angeles County, California, between the City of Los Angeles proper, Orange County, and the Pacific Ocean. The cluster of cities has been termed "Gateway Cities" in that they serve as a "gateway" between the LA and Orange counties, with the city of Cerritos equidistant from Downtown L.A., Long Beach, and Santa Ana in Orange County. As such, the area is central to the Los Angeles-Long Beach-Anaheim, CA Metropolitan Statistical Area (MSA), and has a population of approximately 2,000,000 residents.