The Santa María class of guided missile frigates is the Spanish Navy's designation for six warships based on the United States Oliver Hazard Perry-class frigates. Spanish ships have a slightly bigger beam and were built with a greater weight reserve for future improvements. Other changes from the basic model include Meroka replacing Phalanx and a RAN-12L air search radar to provide low horizon coverage against sea skimmers cueing the Meroka CIWS mount. The Nettunel EW suite replaced the SLQ-32 system fitted aboard US ships. The first ship Santa Maria entered service in 1986.

The Oliver Hazard Perry class is a class of guided-missile frigates named after U.S. Commodore Oliver Hazard Perry, a commander noted for his role in the Battle of Lake Erie. Also known as the Perry or FFG-7 class, the warships were designed in the United States in the mid-1970s as general-purpose escort vessels inexpensive enough to be bought in large numbers to replace World War II-era destroyers and complement 1960s-era Knox-class frigates.