Santa Sofía is a town and municipality in the Department of Boyacá, part of the subregion of the Ricaurte Province, Colombia. The urban centre of Santa Sofía is located at an altitude of 2,387 metres (7,831 ft) on the Altiplano Cundiboyacense, with the highest elevated parts of the municipality, that have a páramo ecosystem, reaching 3,000 metres (9,800 ft). Santa Sofía borders Moniquirá in the north, Gachantivá in the west, Villa de Leyva in the southeast, Sutamarchán in the south, Saboyá in the southwest, and Puente Nacional, Santander in the west.

Boyacá is one of the thirty-two departments of Colombia, and the remnant of Boyacá State, one of the original nine states of the "United States of Colombia".