Santa Trinita is a Roman Catholic church located in front of the piazza of the same name, traversed by Via de' Tornabuoni, in central Florence, Tuscany, Italy. It is the mother church of the Vallumbrosan Order of Monks, founded in 1092 by a Florentine nobleman. South on Via de' Tornabuoni is the Ponte Santa Trinita over the river Arno; across the street is the Palazzo Spini Feroni.

The Santa Trinita Maestà is a panel painting by the Italian medieval artist Cimabue, dating to c. 1288-1292. Originally painted for the church of Santa Trinita, Florence, where it remained until 1471, it is now in the Uffizi Gallery of Florence, Italy. It represents the Madonna enthroned with the Baby Jesus and surrounded by eight angels and, below, four half portraits of prophets.