Santiago Canyon is a canyon and unincorporated community in South Orange County, California. According to the 2000 census, Santiago Canyon has several hundred residents living within its borders. Trabuco Canyon, Silverado Canyon, Modjeska Canyon and Williams Canyon are tributaries of Santiago Canyon. Santiago Creek flows northwest from the canyon, then west into the Santa Ana River. Neighborhoods in Santiago Canyon include Santiago Canyon Estates and Falcon View Estates. The landmark Cook's Corner motorcycle restaurant is also located within Santiago Canyon.

Cook's Corner is an Orange County, California bar built in 1884 that is popular with motorcyclists. It is located between the city of Lake Forest and the unincorporated community of Silverado. Cook's Corner is situated in Trabuco Canyon, California at the intersection of Santiago Canyon Road and Live Oak Canyon Road.