Santiago Metro Line 5 is one of the seven lines that currently make up the Santiago Metro network in Santiago, Chile. It has 30 stations and 29.7 km (18.5 mi) of track. The line intersects with Line 1 at Baquedano station and San Pablo station, with Line 2 at Santa Ana station, with the Line 3 at both Plaza de Armas station and Irarrázaval station, with Line 4 at Vicente Valdés station, and with line 6 at Ñuble station. It will also intersect and the future Line 7 at Baquedano station. Its distinctive colour on the network line map is green.

The Santiago Metro is a rapid transit system serving the city of Santiago, the capital of Chile. It currently consists of seven lines, 143 stations, and 149 kilometres (92.6 mi) of revenue route. The system is managed by the state-owned Metro S.A. and is the first and only rapid transit system in the country.