Santiago Metropolitan Region is one of Chile's 16 first-order administrative divisions. It is the country's only landlocked administrative region and contains the nation's capital, Santiago. Most commercial and administrative centers are located in the region, including Chile's main international airport, Arturo Merino Benítez International Airport.

Arturo Merino Benítez International Airport, also known as Santiago International Airport and Nuevo Pudahuel Airport, located in Pudahuel, 15 km (9.3 mi) north-west of central Santiago, is Chile's largest aviation facility and busiest international airport.