The Sarah Orne Jewett House is a historic house museum at 5 Portland Street in South Berwick, Maine, United States. The house was designated a National Historic Landmark in 1991 for its lifelong association with the American author Sarah Orne Jewett (1849–1909), whose influential work exemplified regional writing of the late 19th century. The house, built in 1774, is a high-quality example of late Georgian architecture. It is now owned by Historic New England, and is open for tours every weekend between June and October, and two Saturdays per month the rest of the year.

South Berwick is a town in York County, Maine, United States. The population was 7,467 at the 2020 census. South Berwick is home to Berwick Academy, a private, co-educational university-preparatory day school founded in 1791.