Highway 18 is a highway in the Canadian province of Saskatchewan. It runs from Highway 13 near Robsart, approximately 65 km (40 mi) east of the Alberta border, to the Manitoba border near Gainsborough, where it becomes Highway 3. It passes through three major communities, all in the eastern quarter of Saskatchewan – Estevan, Oxbow, and Carnduff; it also passes north of the west and east blocks of Grasslands National Park. Highway 18 is about 712 km (442 mi) long, which is the longest east-west highway and second longest highway in Saskatchewan.

Highway 6 is a paved undivided major provincial highway in the Canadian province of Saskatchewan. It runs from Montana Highway 16 at the Canada–US border near the Canada customs port of Regway to Highway 55 near Choiceland. Highway 6 is about 523 km (325 mi) long. The CanAm Highway comprises Saskatchewan Highways from south to north: SK 35, Sk 39, Sk 6, Sk 3, as well as Sk 2. 330 kilometres (210 mi) of Saskatchewan Highway 6 contribute to the CanAm Highway between Corinne and Melfort.