The Sault Ste. Marie Greyhounds are a major junior ice hockey team in the Ontario Hockey League. The Greyhounds play home games at the GFL Memorial Gardens. The present team was founded in 1962 as a team in the Northern Ontario Hockey Association. The Greyhounds name has been used by several ice hockey teams based in Sault Ste. Marie, Ontario, Canada, since 1919.

The Ontario Hockey League is one of the three major junior ice hockey leagues which constitute the Canadian Hockey League. The league is for players aged 16–20. There are currently 20 teams in the OHL: seventeen in Ontario, two in Michigan, and one in Pennsylvania.