Scoresby Sound is a large fjord system of the Greenland Sea on the eastern coast of Greenland. It has a tree-like structure, with a main body approximately 110 km (68 mi) long that branches into a system of fjords covering an area of about 38,000 km2 (14,700 sq mi). The longest of the fjords extends 340–350 km (210-216 mi) inland from the coastline. The depth is 400–600 m (1,310-1,970 ft) in the main basin, but depths increase to up to 1,450 m (4,760 ft) in some fjords. It is one of the largest and longest fjord systems in the world.

Ittoqqortoormiit, formerly known as Scoresbysund, is a settlement in the Sermersooq municipality in eastern Greenland. Its population was 345 as of 2020, and it has been described as one of the most remote settlements on Earth.