Scottsville is a city in Harrison County, Texas, United States. The population was 376 at the 2010 census, up from 263 at the 2000 census. Scottsville's population in 2020 decreased to 334.

Harrison County is a county on the eastern border of the U.S. state of Texas. As of the 2020 United States census, its population was 68,839. The county seat is Marshall. The county was created in 1839 and organized in 1842. It is named for Jonas Harrison, a lawyer and Texas revolutionary.