The Second Baptist Church, located at 441 Monroe Street within Greektown in Detroit, Michigan, is the oldest African-American church in the Midwestern United States. It was designated a Michigan State Historic Site in 1974 listed on the National Register of Historic Places in 1975.

Greektown is a commercial and entertainment district in Detroit, Michigan, located just northeast of the heart of downtown, along Monroe Avenue between Brush and St. Antoine streets. It has a station by that name on the city's elevated downtown transit system known as the Detroit People Mover. Greektown is situated between the Renaissance Center, Comerica Park, and Ford Field.