Dmitry Medvedev's Second Cabinet was the composition of the Russian government from 18 May 2018 to 15 January 2020 under the leadership of Prime Minister Dmitry Medvedev.

The chairman of the government of the Russian Federation, also informally known as the prime minister, is the head of government of Russia and the second highest ranking political office in Russia. Although the post dates back to 1905, its current form was established on 12 December 1993 following the introduction of a new constitution.