The secretary of state for work and pensions, also referred to as the work and pensions secretary, is a secretary of state in the Government of the United Kingdom, with overall responsibility for the business of the Department for Work and Pensions. The incumbent is a member of the Cabinet of the United Kingdom.

The Department for Work and Pensions (DWP) is a ministerial department of the Government of the United Kingdom. It is responsible for welfare, pensions and child maintenance policy. As the UK's biggest public service department it administers the State Pension and a range of working age, disability and ill health benefits to around 20 million claimants and customers. It is the second largest governmental department in terms of employees, and the largest in terms of expenditure (£187bn).