Seiling is a city in Dewey County, Oklahoma, United States. The population was 850 at the 2020 census. The town was named in 1899 for Louis Seiling, a local store owner who had acquired a homestead in the Cheyenne-Arapaho land run of April 1892. The Hobson Town and Improvement Company established a town called Hobson, but the name was changed to Seiling in January 1899. It incorporated in 1909. Seiling is now the largest city in Dewey County. Their girls basketball team has also won the Oklahoma State Championship four times in a row (2016-2019).

Dewey County is a county in the western part of the U.S. state of Oklahoma. As of the 2020 census, the population was 4,484. Its county seat is Taloga. The county was created in 1891 as "County D". In an 1898 election, county voters chose the name Dewey, honoring Admiral George Dewey.