A seraglio, serail, seray or saray is a castle, palace or government building which was considered to have particular administrative importance in various parts of the former Ottoman Empire.

The Topkapı Palace, or the Seraglio, is a large museum and library in the east of the Fatih district of Istanbul in Turkey. From the 1460s to the completion of Dolmabahçe Palace in 1856, it served as the administrative center of the Ottoman Empire, and was the main residence of its sultans.