Serhetabat is a city in Tagtabazar District, Mary Province, Turkmenistan. Serhetabat lies in the valley of the Kushka River. The population was 5,200 in 1991. It is immediately opposite Torghundi, Afghanistan, with which it is connected by a road and a 1,520 mm gauge railway.

Mary Region is one of five provinces in Turkmenistan. It is located in the south-east of the country, bordering Afghanistan. Its capital is the city of Mary. Its area is 87,150 km2 (33,650 sq mi) and population 1,613,386. The average population density is about 15 persons per square kilometer, but it reaches 150–200 per square kilometer in the most developed oases.