The Settebello was a famous Italian high-speed express train that linked Milano Centrale in Milan with Roma Termini station in Rome, via Bologna and Florence. Introduced in 1953, it was operated by the Italian State Railways (FS) and used the distinctive ETR 300-type electric multiple unit trainsets, featuring observation lounges at the front and rear of the train. When introduced, it "set a standard of speed and luxurious travelling accommodation previously unknown in Italy [and] rivalling anything else on European rails." It was a Trans Europ Express (TEE) from 1974 until its withdrawal, in 1984.

The Trans Europ Express, or Trans-Europe Express (TEE), was an international first-class railway service in western and central Europe that was founded in 1957 and ceased in 1995. At the height of its operations, in 1974, the TEE network comprised 45 trains, connecting 130 different cities, from Spain in the west to Austria in the east, and from Denmark to Southern Italy.