The Shanghai–Kunming high-speed railway is a high-speed railway line. It was built in stages and completed on 28 December 2016. It is part of the CRH's system of passenger-dedicated lines, beginning in Shanghai and ending in Kunming, the capital of Yunnan Province. Following a fairly similar route to the older "conventional" Shanghai–Kunming Railway, the Shanghai–Kunming high-speed railway passes through four more provincial capitals, the cities of Hangzhou, Nanchang, Changsha, and Guiyang.

Guiyang is the capital of Guizhou province of the People's Republic of China. It is located in the center of the province, situated on the east of the Yunnan–Guizhou Plateau, and on the north bank of the Nanming River, a branch of the Wu River. The city has an elevation of about 1,100 meters (3,600 ft). It has an area of 8,034 square kilometers (3,102 sq mi). At the 2020 census, its population was 5,987,018, out of whom 4,506,134 lived in the six urban districts.